Effect of Healthy Lifestyle Promotion on Anthropometric Variables, Eating Behavior and Cardiometabolic Risk Factors in Women with Polycystic Ovarian Syndrome

Latifa Imen  Benharrat; Azzedine  Senouci; Wassila  Benhabib; Khedidja  Mekki

doi:10.51745/najfnr.4.9.S46-S53

Effect of Healthy Lifestyle Promotion on Anthropometric Variables, Eating Behavior and Cardiometabolic Risk Factors in Women with Polycystic Ovarian Syndrome

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Nutrition, Metabolism, and Prevention of NCDs

DOI https://doi.org/10.51745/najfnr.4.9.S46-S53

Issue Vol. 4 No. 9 (2020): Special Issue: Nutritional Situation In Africa. An Update (UPNIA-2020)

Submitted 2020-09-16

Published 2020-12-24

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Background: In women with Polycystic Ovarian Syndrome (PCOS), metabolic abnormalities are common, including insulin resistance, obesity, and dyslipidemia, suggesting an increased risk for cardiovascular disease (CVD).

Aims: To evaluate the effect of healthy lifestyle promotion on eating behavior and metabolic biomarkers in women with PCOS.

Subjects and Methods: The study was carried out in 102 women (30±7 years) with PCOS. Patients received nutritional counseling based on Mediterranean diet principles and recommendations to practice a regular physical activity, and were followed up during six weeks. Dietary survey and biomarkers analysis were assessed at baseline (T0), after three weeks (T1) and 6 weeks (T2).

Results: After six weeks of intervention, there was a significant decrease in total energy intake by (-30%) at T1 and (-32%) at T2 (p˂0.001), compared to baseline. Significant decrease was recorded in carbohydrates, proteins and lipids intake at T1 and T2 (p˂0.001). An increase in monounsaturated fatty acid intake was noted at T1 and T2 (p˂0.001). The body mass index (BMI) was diminished at T2 (p˂0.01), and waist circumference at T1 and T2 (p˂0.001). Glucose values decreased at T1 (p˂0.05) and T2 (p˂0.001). Total cholesterol decreased at T1 (p˂0.05) and T2 (p˂0.01). HDL-C increased at T1 (p˂0.001) and T2 (p˂0.001), when CRP values remained unchanged. A decrease in Thiobarbituric acid reactive substances concentrations was observed at T1 and T2 (p˂0.05). Superoxyde Dismutase, Catalase activities and thiols amount increased at T2 (p˂0.001).

Conclusion: In the long term, healthy lifestyle promotion could be beneficial to prevent or reverse the clustering of metabolic abnormalities and prevent CVD in women with PCOS.

Keywords

Polycystic Ovary Syndrome Metabolic Abnormalities Healthy Lifestyle Mediterranean Diet Cardiometabolic Risk

Latifa Imen Benharrat

Laboratory of Clinical and Metabolic Nutrition, University Oran 1, Oran 31100
Azzedine Senouci

Laboratory of Clinical and Metabolic Nutrition, University Oran 1, Oran 31100
Wassila Benhabib

Department of Epidemiology, University Hospital of Oran, Oran 31037
Khedidja Mekki

Laboratory of Clinical and Metabolic Nutrition, University Oran 1, Oran 31100

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Benharrat, L. I. ., Senouci, A. ., Benhabib, W. ., & Mekki, K. . (2020). Effect of Healthy Lifestyle Promotion on Anthropometric Variables, Eating Behavior and Cardiometabolic Risk Factors in Women with Polycystic Ovarian Syndrome. The North African Journal of Food and Nutrition Research, 4(9), S46-S53. https://doi.org/10.51745/najfnr.4.9.S46-S53

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