Overview on Cardiometabolic Associated Factors in Patients with COVID-19: A Narrative Review

Coronavirus disease 2019 (COVID-19) increases the risk of several cardiovascular diseases (CVDs) such as acute myocardial injury. Vascular dysfunctions are important drivers of CVDs. A variety of risk factors promotes the development and progression of CVDs including, overweight and obesity, arterial hypertension, physical inactivity, smoking, unhealthy diet, overconsumption of alcohol, dyslipidemia, atherosclerosis and diabetes mellitus. However, nearly all of these risk factors are modifiable by antihypertensive, antidiabetic, or lipid-lowering medication and lifestyle changes. Others such as age or genetic factors cannot be modified. Moreover, infection and inflammation have been shown to increase the risk of CVDs. The COVID-19 pandemic yielded a new perspective to this field. Cardiometabolic events, diseases, risk factors and COVID-19 are strongly intertwined. An increased CVDs risk through multifactorial mechanisms has been observed in COVID-19 patients. Furthermore, a higher rate of infection with COVID-19, severe COVID-19, and bad outcome has been demonstrated in patients with established cardiometabolic disorders and vascular risk factors. Summary at present, we suggest that regular interactions between healthcare professionals and patients should include education on COVID-19 and on primary and secondary vascular prevention in order to minimize the burden of the virus in our susceptible populations.

Keywords

COVID-19 SARS-CoV-2 Cardiovascular Diseases Endothelial Dysfunction Metabolic Syndrome Systemic Inflammation
  • Walid Hassene Hamri
    1. Department of Biology, Faculty of Natural and Life Sciences, Djillali Liabes University, Sidi-Bel-Abbes, Algeria. 2. Laboratory of Molecular Microbiology Proteomics and Health, Djillali Liabes University, Sidi-Bel-Abbes
  • Mustapha Diaf
    Department of Biology, Faculty of Natural and Life Sciences, Djillali Liabes University, Sidi-Bel-Abbes

How to Cite

Hamri, W. H. ., & Diaf, M. . (2021). Overview on Cardiometabolic Associated Factors in Patients with COVID-19: A Narrative Review. The North African Journal of Food and Nutrition Research, 4(10), S25-S31. https://doi.org/10.51745/najfnr.4.10.S25-S31

1. Zhu, N., Zhang, D., Wang, W., Li, X., Yang, B., Song, J., Zhao, X., Huang, B., Shi, W., Lu, R., Niu, P., Zhan, F., Ma, X., Wang, D., Xu, W., Wu, G., Gao, G. F., Tan, W., & China Novel Coronavirus Investigating and Research Team (2020). A Novel Coronavirus from Patients with Pneumonia in China, 2019. The New England Journal of Medicine, 382(8), 727–733. https://doi.org/10.1056/NEJMoa2001017

2. Li, Q., Guan, X., Wu, P., Wang, X., Zhou, L., Tong, Y., Ren, R., Leung, K., Lau, E., Wong, J. Y., Xing, X., Xiang, N., Wu, Y., Li, C., Chen, Q., Li, D., Liu, T., Zhao, J., Liu, M., Tu, W., … Feng, Z. (2020). Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia. The New England Journal of Medicine, 382(13), 1199–1207. https://doi.org/10.1056/NEJMoa2001316

3. World Health Organization official website accessed in December 2020. URL address: https://covid19.who.int/

4. Huang, C., Wang, Y., Li, X., Ren, L., Zhao, J., Hu, Y., et al. (2020). Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 395,497–506. https://doi.org/10.1016/S0140-6736(20)30183-5

5. Myers, L. C., Parodi, S. M., Escobar, G. J., & Liu, V. X. (2020). Characteristics of hospitalized adults with COVID-19 in an integrated health care system in California. JAMA, 323(21), 2195. https://doi.org/10.1001/jama.2020.7202

6. Grasselli, G., Zangrillo, A., Zanella, A., Antonelli, M., Cabrini, L., Castelli, A., Cereda, D., Coluccello, A., Foti, G., Fumagalli, R., Iotti, G., Latronico, N., Lorini, L., Merler, S., Natalini, G., Piatti, A., Ranieri, M. V., Scandroglio, A. M., & Storti, E. (2020). Baseline characteristics and outcomes of 1591 patients infected with SARS-Cov-2 admitted to ICUs of the Lombardy region, Italy. JAMA, 323(16), 1574. https://doi.org/10.1001/jama.2020.5394

7. Scutelnic, A., & Heldner, M. R. (2020). Vascular Events, Vascular Disease and Vascular Risk Factors—Strongly Intertwined with COVID-19. Current Treatment Options in Neurology, 22(11), 1-16. https://doi.org/10.1007/s11940-020-00648-y

8. Ferrari, F. (2020). COVID-19: updated data and its relation to the cardiovascular system. Arq. Bras. Cardiol. 114, 823–826. https://doi.org/10.36660/abc.20200215

9. Alhogbani T. (2016). Acute myocarditis associated with novel Middle east respiratory syndrome coronavirus. Annals of Saudi Medicine, 36(1), 78–80. https://doi.org/10.5144/0256-4947.2016.78

10. Zheng, S., Fan, J., Yu, F., Feng, B., Lou, B., Zou, Q., Xie, G., Lin, S., Wang, R., Yang, X., Chen, W., Wang, Q., Zhang, D., Liu, Y., Gong, R., Ma, Z., Lu, S., Xiao, Y., Gu, Y., … Liang, T. (2020). Viral load dynamics and disease severity in patients infected with SARS-Cov-2 in Zhejiang province, China, January-March 2020: Retrospective cohort study. BMJ, m1443. https://doi.org/10.1136/bmj.m1443

Similar Articles

1-10 of 186

You may also start an advanced similarity search for this article.

Most read articles by the same author(s)

Downloads 586

-

Views 1315

-

Country (Top 10)